Endocrine Abstracts

Introduction: Fetal goiter is a rare condition. The incidence of goitrous hypothyroidism is 1/30 000–50 000 live births. We describe a case of antenatal fetal goiter that vanished upon delivery and was not detected in the newborn. The case report is followed by a discussion wherein we review the literature on thyroid problems in pregnancy and management of fetal goiter.Case report: A 27-year-old known hypothyroid woman with bichorial biamniotic preg...

Patients with histology confirmed acromegaly who have undergone trans-sphenoidal surgery and radiotherapy often have active acromegaly despite no evidence of adenoma on MRI. Currently 111In Octreotide, a radioactive tracer, is used in the assessment of neuroendocrine tumours, with 70-90 percent sensitivity for detection. Studies to date however have not looked at 111In Octreotide as an alternative measure to assess patients who present with biochemically active acromegaly desp...

Studies show conflicting results regarding possible excess risk of atypical fractures associated with bisphosphonate (BSP) use. Since BSP reduces bone remodeling, they freeze the skeleton allowing accumulation of microcracks over time leading to atypical fractures. We present two cases of atypical fracture and discuss on monitoring therapy and drug holiday in chronic BSP users.Methods: Over the period of last 8 months we diagnosed two cases of alendronat...

Introduction: Insulinomas are the commonest hormone-secreting tumor of gastrointestinal tract. Presentation is usually insidious with neuroglycopenia and fasting hypoglycemia. Many patients do not report adrenergic symptoms of hypoglycemia and present with neurological or psychiatric manifestations that often lead to misdiagnosis. The symptoms of insulinoma lack specificity, including various seizure disorders, personality change, bizarre behavior, amnesia, convulsions, and in...

Introduction: Primary Hypoparathyroidism presents most commonly in childhood to early adolescence. Disease may be familial or sporadic.Most commonly hypoparathyroidism is secondary to neck operations especially Thyroid surgeries. Primary can be congenital eg- Digeorge syndrome or inherited by AD, AR or X linked mediated.We report 2 cases of late onset seizure due to Digeorge syndrome and Autosomal Dominant Hypoparathyroidism in a elderly lady.Case Report...